Ytpfamily:Sul/Sfp family

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Yeast permeases in YTP family Sul/Sfp family

Gene name Description Sublocation
YGR125W Edit YGR125W data Protein distantly related to sulfate permeases unknown
YPR003C Edit YPR003C data Protein similar to sulfate permease - unknown function unknown
SUL1 Edit SUL1 data Sulfate permease I plasma membrane
SUL2 Edit SUL2 data Sulfate permease II plasma membrane

Protein alignment for family Sul/Sfp family

SUL2            -------MsRegypnFeeveiPdFqetNntvpDlDdlEleYdqYknnEnndtfnDkdles
SUL1            -------MsRkssteYvh---------NqedaDiEvFEseYRtYrEsEaa----EnrdGl
YPR003C         mtsnnsllGR-grmsYsstapPrF---krsvdqrDtFsdnF-------------Dydkds
YGR125W         -------MGRtirrrrsnsslseaisvslginqdssvnkmhRasvsamspplcrsymsGf

SUL2            nsvaKhnavnsskgvkgSKidyfNpSdvsLydNSvSqf---------------EEtTvSl
SUL1            hNgdEenwkvNsS---kqKFgvtknelsdVlydSipay---------------EESTvtl
YPR003C         sNrGrtyiaasnS---tTgvpppNnSrsgctnNtnNtn---------------ntSntSn
YGR125W         ftgGnspminNlS---dSKlpisNkqhpkVihgSeNlhrqtaqlsnefcsssvEEnspti

SUL2            KEYyD-------------HSIrshLtvkgAcsYLksVFPiI--------------NWLPh
SUL1            KEYyD-------------HSIknNLtaksAgsYLvsLFPiI--------------kWfPh
YPR003C         tnnnD--------------SvDENtvfEtlpyYLpcf------------------SWLPE
YGR125W         KDYmDiigngdrkddqsmrtIEENIdeEySdeYsrlLlspassnvdddrnrglqnSsLPE

SUL2            YN--FswftaDLiAGITI---gcvLvPQSMSY-AQVAtLpa--qyGLYSsfIGAYsYs--
SUL1            YN--FtwgYaDLvAGITV---gcvLvPQSMSY-AQIAsLsP--eyGLYSsfIGAFiYs--
YPR003C         Yt--FnklWgDviAGIsV---asfqiPlALSYttsIAHVpP--lcGLYSlaIspFvYG--
YGR125W         ledgyaggYqsLrpshnlrfrprnLwhmctSfpskfAHylPaavlGLllnildAlsYGmi

SUL2            fFaTSKDVC--IGPvAVMSLqTAKVIA--------------------dVTakYpDgdsaI
SUL1            LFaTSKDVC--IGPvAVMSLqTAKVIA--------------------EVlkkYpEdqtev
YPR003C         IlgSvpqmi--VGPeSaISLvvgQav---------------------EsitlhkEnvslI
YGR125W         IFpiTEpVfshlGPtgIsmfyiStIIsqavysggwssfpsgigsemiEITpfYhtmalaI

SUL2            t-------gPvIATTl------aLLCGIIsaavGfLRLGFLVeLISlNAvaGFmTGsAFn
SUL1            t-------aPIIATTl------cLLCGIvatglGiLRLGFLVeLISlNAvaGFmTGsAFn
YPR003C         d----------IsTvI------tfvsGtIllfsGisRfGFLgnVLSkalLrGFISsvglv
YGR125W         kealagnddeIItTTIfcyvissMLtGVvfyalGkLRLGkiVgffprHiLiGcIgGvgYf

SUL2            IlwGqVpAlMgYNslVnTRaAtYKvvieTlkhLpDTKldAvFGLIPLfl-----LYVwKW
SUL1            IIwGqIpAlMgYNslVnTReAtYKvvinTlkhLpnTKldAvFGLIPLvI-----LYVwKW
YPR003C         mIInsliSeLklDKFlvslpqhYhtPFekilFLiDy-apAqY-hIPtaIfsgccLiVL--
YGR125W         LIItgIevttrvaKF------eYswPFfSglF-tDydtlAkw-LlPVll-----tvVL--

SUL2            WCGTYGpRLnDR----YnsknPRLhkiIKwtYFyAqasRNgIiIiVFTcIgwaITrgksk
SUL1            WCGTFGitLaDR----YyRNqPKVanrLKsfYFyAqamRNavvIvVFTAIswSITrNkss
YPR003C         ----FltRLlkRklmkYhKs---------aiFFPd------ILLvVivtIliSmkfNlkh
YGR125W         ----iGtQ---R----YfKN---------slvlPSfyiltlvLfhfivAIiptLSldalr

SUL2            serpISIlGsvPSg----LKeVgVfhVppGLmskLgPnlpAsiIVllLEhiaiSKSFG--
SUL1            KdrpISIlGtvPSg----LneVgVmKIpdGLLsnMsseipAsiIVlvLEhiaiSKSFG--
YPR003C         RyG-ISIIGDfsmdnFDeLKn-pltRprrkLIpdLfsaslivaMLgFfEsttaSKSlG--
YGR125W         QaGwIfpIaNsdSkwYDhyRlfnVhKVhwsLVlqqiPtmmAltffgiLhvpinvpalams

SUL2            -RInDYkVvPDQELIAiGVSNLlgTFFnAYPAtGsFSRSaLkAKCnvRtPlSGLFsGsCv
SUL1            -RInDYkVvPDQELIAiGVTNLigTFFhsYPAtGsFSRSaLkAKCnvRtPFSGVFtGgCv
YPR003C         -ttyNltVssnrELvAlGfmNIviSlFGAlPAfGgygRSkinAlsGAQSvmSGVFmGviT
YGR125W         lQMdkYdV--DrELIAhGySNfFsgllGsvqnylvyTnSvLfiRaGAdSPFaGfllialT

SUL2            LLaLyCltgaFfyIPkATLSAVIihAvsDLLasyqtt-WnFWKmNplDfIcFIVTVl-IT
SUL1            LLaLyCltdaFfFIPkATLSAVIihAvsDLLtsyktt-WtFWKtNplDcIsFIVTVF-IT
YPR003C         LItmnlllqfvhyIPncvLSvIttiigisLLeEvpgDikfhlrcggFselfvfavtFctT
YGR125W         icimiigpviisFIPicivgSlIfllgyELLvEalvDtWn--KlNrFEyltvVIiVFtMg

SUL2            vFaSIEdGIyFAMCWSCamLIlk--------vAfpAGKFlGrVevAEVtdayVrpD-sDv
SUL1            vFsSIEnGIyFAMCWSCamLllk--------qAfpAGKFlGrVevAEVlnptVQeD-IDa
YPR003C         IFySIEaGIcigcvYSiinIIkhSaKsriqilArvAG--tsNftnlDdymmnmkrNsLDv
YGR125W         IFdfv-lGIivgIliaCfsflvdStK-----lqtinGeynGNVarStVyrdyVQtkfLDg

SUL2            V-------syVsEnnNgistledggeddkesstkyvtNssKKIEtnvQtkGfdspsssis
SUL1            V-------issnElpNeL---------------------nKqVkstvEv---------lp
YPR003C         eGtEeiegcmIvripepL-------------tFtnseDlKqRlDRiery-Gsskihpgrk
YGR125W         IGeQ----iyVlklqNlL-------------fFgtiisiEeKIERllQi---------sn

SUL2            qpRiKyhtKWIpFDhkytRElNpDvqilPppdgvl-vYRlsesYTYLnCsRhyniIteev
SUL1            apeyKfsVKWVpFDhGysRElNIntTvrPpppgvi-vYRlgdsFTYvnCsRhyDiIfdRi
YPR003C         slRsKdsIKyViFDlGgmt--sIDsSAaqvleeIitsYKrrnvFiYLvnvsinDkvrrRl
YGR125W         kdatKrrIKylilDfkninadNIDySAaegfnrIkrftetkrikliissiKerDrIynaF

SUL2            kKvTRRGqLirhrKkSDRPWNDPgpWeaPaFLkNLkfwKKRendpeSmenapstsv----
SUL1            keeTRRGqLitlrKkSDRPWNDPgEWkmPdsLkSLfkfKrhSattnSDlpiSNgsS----
YPR003C         fKa---GvaasvE---------------------------RAqannNEnntSNtfS----
YGR125W         nnv---GlLndvElfaD--lNsalEWceneFLfqykqlrKKAkerleEgkqNNvvSavia

SUL2            ------------------DvEr--------------------------dDrPLLKilClD
SUL1            ------------------NGET--------------------------yeKPLLKvvClD
YPR003C         -----------------daGET--------------------------------------
YGR125W         atknkkidtignglnrgsNGdTarnlmslptntprnyqilsvaqnvfvnDEqavKnfkke

SUL2            FSQvAQtdaTALqSLvDLRKaInqYAD--RQvEFHFvGiISPWvkRgliSrg--------
SUL1            FSQvAQVdsTAvqSLvDLRKavnrYAD--RQvEFHFaGiISPWikRslLSvk--------
YPR003C         ---------------------------------------ySPyFdsi-------------
YGR125W         ykddepVlpilLfaLkqyRpdIisevqkvRekEikFwaqLcPyFtRrrLasqshllhadn

SUL2            -----------------fGTLNEeYS-----DesIVaGHtSYHVARVPQgEenp------
SUL1            -----------------fGTtNEeYS-----DdsIIaGHsSFHVAKVlKdDvdytDeDSr
YPR003C         -----------------daaLyEi-------EKmkIkGnn------VPnnDs--------
YGR125W         ifflvetgmlkatyelpqGTLyEifSngtcfgKiIapGna------mPReqkltiEtETd

SUL2            ------EkySvyTAsGTNLpFF--------------HiDIPDFAKWDi
SUL1            istsysnyeTlcaAtGTNLpFF--------------HiDIPDFSKWDv
YPR003C         ------EsfmsnTlfnSsLv----------------------------
YGR125W         svlwviDssSlnklkedNLalyvevalmvmcikdtrfkellgytlvsA

Multiple alignment realised using Muscle v3.6
Edgar, R.C. Nucleic Acids Res 32(5), 1792-97

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