Sublocation:Secretory pathway membrane

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(Synonyms : secretory and endocytic pathways membranes)

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Yeast permeases in compartment Secretory pathway membrane

Gene name Description Sublocation
AQR1 Edit AQR1 data Vesicular amino-acid transporter involved in excretion of homoserine, threonine and other amino acids vesicular membrane
ARN1 Edit ARN1 data Transporter of ferrichrome-type siderophores late endosome membrane
ARN2 Edit ARN2 data Transporter of the fungal siderophore triacetylfusarinine C endosomal membrane
ATG22 Edit ATG22 data Vacuolar membrane transporter catalysing efflux of amino acids during autophagy vacuolar membrane
ATX2 Edit ATX2 data Putative Golgi transporter involved in homeostasis of manganese ions Golgi membrane
AVT1 Edit AVT1 data Transporter essential for the uptake of tyrosine, glutamine, asparagine, isoleucine and leucine in isolated vacuoles vacuolar membrane
AVT3 Edit AVT3 data Transporter mediating the release of tyrosine, glutamine, asparagine, isoleucine and leucine from the vacuole to the cytosol vacuolar membrane
AVT4 Edit AVT4 data Transporter mediating the release of tyrosine, glutamine, asparagine, isoleucine and leucine from the vacuole to the cytosol vacuolar membrane
AVT6 Edit AVT6 data Transporter mediating the release of glutamate and aspartate from the vacuole to the cytosol vacuolar membrane
AVT7 Edit AVT7 data Protein similar to plant amino-acid transporters and mammalian vesicular GABA transporter - unknown function vacuolar membrane
BAT1 Edit BAT1 data Vacuolar, `full-size` ABC protein transporting bile acids vacuolar membrane
BPT1 Edit BPT1 data Vacuolar `full-size` ABC transporter responsible for vacuolar sequestration of glutathione-S-conjugates vacuolar membrane
CCC1 Edit CCC1 data Proposed vacuolar iron transport protein vacuolar membrane
CCC2 Edit CCC2 data P-type ATPase involved in export of Cu++ from the cytosol into intracellular, secretory compartments Golgi and endosomal membrane
COT1 Edit COT1 data Vacuolar zinc (and possibly other metals) transporter vacuolar membrane
DNF3 Edit DNF3 data Golgi membrane P-type ATPase acting as a phospholipid translocase (flippase) trans-Golgi membrane
DRS2 Edit DRS2 data Golgi membrane P-type ATPase acting as a phospholipid translocase (flippase) trans-Golgi membrane
FLC1 Edit FLC1 data Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance endoplasmic reticulum
FTH1 Edit FTH1 data Vacuolar transporter involved in iron efflux out of the vacuole - forms a comple with Fet5 vacuolar membrane
FUN26 Edit FUN26 data Broad-specificity nucleoside and nucleobase transporter of internal membranes - similar to human placental equilibrative nucleoside transporter 1 vacuolar membrane
GEF1 Edit GEF1 data Chloride channel of Golgi and endosomal compartments Golgi and endosomal membrane
GEX2 Edit GEX2 data Plasma membrane and vacuolar membrane glutathione/H+ antiporter vacuolar membrane
GOG5 Edit GOG5 data Nucleotide-sugar permease of the Golgi - promotes transport of GDP-mannose Golgi membrane
HUT1 Edit HUT1 data UDP-galactose transporter located in the Golgi Golgi membrane
KHA1 Edit KHA1 data Intracellular (probably Golgi apparatus) antiporter Golgi membrane
MCH1 Edit MCH1 data Vacuolar transporter similar to mammalian monocarboxylate transporters - unknown biological function vacuolar membrane
MCH4 Edit MCH4 data Protein similar to mammalian monocarboxylate transporters - unknown biological function vacuolar membrane
MSC2 Edit MSC2 data Protein similar to the Cot1p and Zrc1p metal vacuolar transporters - affects cellular distribution of zinc nuclear and ER membrane
NCR1 Edit NCR1 data Vacuolar transport protein involved in sterol homeostatis and trafficking vacuolar membrane
NEO1 Edit NEO1 data P-type ATPase similar to Drs2p, a proposed aminophospholipid translocase (flippase) - unknown function Golgi and endosomal membrane
NHX1 Edit NHX1 data Na+/H+ exchanger of the prevacuolar compartment - involved in salt tolerance late endosome membrane
PMC1 Edit PMC1 data Vacuolar P-type ATPase transporting Ca++ into the vacuole vacuolar membrane
PMR1 Edit PMR1 data Ca++-transporting P-type ATPase located in Golgi Golgi membrane
SMF3 Edit SMF3 data Vacuolar protein similar to the Smf1 manganese transporter - proposed role in mobilization of vacuolar iron vacuolar membrane
SPF1 Edit SPF1 data P-type ATPase of the endoplasmic reticulum - involved in calcium homeostasis endoplasmic reticulum
SYG1 Edit SYG1 data Putative transport protein of inner membranes vacuolar membrane
TPO5 Edit TPO5 data Protein involved in excretion of putrescine and spermidine - present in Golgi and endosomal membranes Golgi and endosomal membrane
VBA1 Edit VBA1 data Vacuolar transporter involved in vacuolar sequestration of lysine and histidine - likely acts as an H+ antiporter vacuolar membrane
VBA2 Edit VBA2 data Vacuolar transporter involved in vacuolar sequestration of arginine, histidine, lysine and tyrosine - likely acts as an H+ antiporter vacuolar membrane
VBA3 Edit VBA3 data Vacuolar transporter involved in vacuolar sequestration of histidine and lysine - likely acts as an H+ antiporter vacuolar membrane
VBA4 Edit VBA4 data Putative substrate-H+ antiporter - unknown biological function vacuolar membrane
VCX1 Edit VCX1 data Vacuolar Ca++/H+ exchanger vacuolar membrane
VHC1 Edit VHC1 data Vacuolar, probable K+-Cl- cotransporter of the CCC (electroneutral cation-Cl(-) cotransporters) family vacuolar membrane
VNX1 Edit VNX1 data Vacuolar Na+(K+)/H+ exchanger vacuolar membrane
YBR241C Edit YBR241C data Protein of the sugar transporter superfamily - unknown biological function vacuolar membrane
YCF1 Edit YCF1 data Vacuolar `full-size` ABC transporter responsible for vacuolar sequestration of glutathione-S-conjugates vacuolar membrane
YEA4 Edit YEA4 data Uridine diphosphate N-acetyl glucosamine transporter of the endosplasmic reticulum membrane endoplasmic reticulum
YHC3 Edit YHC3 data Vacuolar membrane protein with proposed role in arginine tranport - mutations in the human ortholog (Btn1) causes Batten disease vacuolar membrane
YKE4 Edit YKE4 data Endoplasmic reticulum bidirectional zinc transporter endoplasmic reticulum
YML018C Edit YML018C data Vacuolar putative transporter of unknown function vacuolar membrane
YML038C Edit YML038C data Putative transporter of the triose phosphate translocator family - unknown function secretory pathway membrane
YPK9 Edit YPK9 data Vacuolar P-type ATPase - proposed role in sequestration of divalent heavy metal ions. Similar to human lysosomal ATP13A2 ATPase which is altered in patients with Kufor-Rakeb syndrome vacuolar membrane
YPQ1 Edit YPQ1 data Probable basic amino acid exporter of the vacuolar membrane vacuolar membrane
YPQ2 Edit YPQ2 data Vacuolar transporter of the PQ-loop family involved in export of arginine, canavanine and possibly other basic amino acids stored in the vacuole. vacuolar membrane
YPQ3 Edit YPQ3 data Vacuolar transporter of the PQ-loop family involved in export of lysine and possibly other basic amino acids stored in the vacuole. vacuolar membrane
YVC1 Edit YVC1 data Vacuolar, Ca++-activable, cation channel vacuolar membrane
ZRC1 Edit ZRC1 data Vacuolar transporter of zinc (and possibly other metals) vacuolar membrane
ZRG17 Edit ZRG17 data Zinc-regulated transporter of the endoplasmic reticulum endoplasmic reticulum
ZRT3 Edit ZRT3 data Vacuolar zinc efflux protein vacuolar membrane
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